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生物颗粒光声功率谱的有限元数值模拟研究

李勇 [1], 方晖 [2],
[1] 晋中学院,太原,中国
[2] 深圳大学,深圳,中国

定量分析生物颗粒形态的变化可以为疾病诊断提供依据。例如血红细胞形态的变化常常会伴随有相应的血液疾病[1],细胞的癌变常常伴随有细胞核形态的变化[2]等等。无标记的光学显微成像技术已经可以对生物颗粒的尺度和形状进行直接测量。光声显微成像技术(PAM)利用生物颗粒固有的吸光本领,已经可以对单个生物颗粒(如细胞和细胞器)进行成像[3]。 最近,光声流式仪(the photoacoustic flow-cytometry)已经实现了对单个生物颗粒进行连续检测[4]。然而,为了在大量的生物颗粒中快速检测生物颗粒的形貌,最好的方法是并非对其进行直接成像,而是采用高频光声显微技术[5],它的分辨率来源于实际测量与光声功率谱的分析。 光声功率谱分析需要通过计算建模来获取。我们使用 COMSOL Multiphysics® 有限元分析软件的声学模块用来建模 MFC7 细胞核的光声功率谱 ...

The Effect of Space Charge due to the Auto-Ionization of Neutral, Hydrogenic States in Point-Contact Germanium Detectors at MilliKelvin Temperatures - new

D. Faiez[1], N. Mirabolfathi[1], B. Sadoulet[1], K. M. Sundqvist[2]
[1]Department of Physics, University of California - Berkeley, Berkeley, CA, USA
[2]Department of Electrical & Computer Engineering, Texas A&M University, College Station, TX, USA

A class of semiconducting detectors, operated at temperature T~50mK, has direct application to the search for dark matter particle, when are able to simultaneously measure both the ionization and phonons created by particle interactions. We explore the effect of space charge accumulation in a germanium p-type point contact detector which arises due to the auto-ionization of hydrogenic ...

Optimizing the Fluorescence of Diamond Color Centers Encapsulated into Core-Shell Nano-Resonators

M. Csete [1], L. Z. Szabó [1], A. Szenes [1], B. Bánhelyi [2], T. Csendes [2], G. Szabó [1]
[1] Department of Optics and Quantum Electronics, University of Szeged, Szeged, Hungary
[2] Institute of Informatics, University of Szeged, Szeged, Hungary

INTRODUCTION Enhancement of a single-photon emission is a great demand in recent science and applications, including development novel class of light sources, encoded information transfer and biological imaging [1, 2, 3]. Fluorescence can be improved through excitation and emission enhancement. Improvement of these two processes can be realized by using the near-field enhancement accompanying ...

Modeling of a Dielectric Barrier Discharge Lamp for UV Production

S. Bhosle, R. Diez, H. Piquet, D. Le Thanh, B. Rahmani, D. Buso
Université de Toulouse, Toulouse, France

Excilamps are artificial Ultraviolet sources based on the emission of excimers or exciplexes. The latter are excited states of weakly bound rare gas or halide/rare gas atoms which emit a photon in the UV region when they dissociate. Dielectric Barrier Discharge (DBD) excilamps are promising UV sources for the future, provided the coupling between their power supply is optimized. The model ...

Light Scattering Simulation of Nano-objects on the Surface of Silicon Wafers by 3D Finite Element Method

Y. Oshikane, T. Higashi, N. Taniguchi, M. Nakano, and H. Inoue
Dept. of Prec. Sci. and Technology
Grad. School of Eng.
Osaka University
Japan

Nanotechnology is rated as a key technology of the 21st century. In the field of nano-optics already at present, state-of-the-art scientific experiments and industrial applications exhibit nanometer to sub-nanometer design tolerances. This motivates the development and application of fast and accurate simulation tools for these fields or electromagnetic (EM) field.

A Study on the Suitability of Indium Nitride for THz Plasmonics

A. Shetty[1], K. J. Vinoy[1], S. B. Krupanidhi[2]
[1]Electrical Communication Engineering, Indian Institute of Science, Bangalore, India
[2]Materials Research Centre, Indian Institute of Science, Bangalore, India

As interest in the electromagnetic spectrum expands towards the infrared and terahertz range, the distinct advantages of using semiconductors instead of metals for plasmonic applications must be understood. Plasmonic resonances in gold (Au) and indium nitride (InN) gratings are studied, in the terahertz (?=30µm) regime. The electromagnetic properties of Au and InN are described by the Drude ...

An All-Purpose Full-Vectorial Finite Element Model for Arbitrarily Shaped Crossed-Gratings

G. Demésy[1], F. Zolla[1], A. Nicolet[1], and M. Commandré[1]
[1]Institut Fresnel, Université Aix-Marseille III, École Centrale de Marseille, France

We demonstrate the accuracy of the Finite Element Method (FEM) to characterize an arbitrarily shaped crossed-grating in a multilayered stack illuminated by an arbitrarily polarized plane wave under oblique incidence. To our knowledge, this is the first time that 3D diffraction efficiencies are calculated using the FEM. The method has been validated using classical cases found in the literature. ...

Cancer Detection Using Coagulation Therapy with Coaxial Antenna - new

S. M. Ali[1], A. K. Jha[1], S. Mahapatra[1], M. Panigrahi[1]
[1]Trident Academy of Technology, Bhubaneswar, Odisha, India

Nearly seven lakh Indians die of cancer, while over 10 lakh are newly diagnosed with some form of the disease every year. Surgical resection is not always feasible in patients with hepatocellular carcinoma. Microwave Coagulation Therapy (MCT) has been used as an alternative to resection and its efficiency has been evaluated in tissue microwave irradiation from a dipole antenna causes water ...

Coupling Picosecond Terahertz Pulses to a Scanning Tunneling Microscope

P. H. Nguyen [1], C. Rathje [2], G. J. Hornig [1], V. Jelic [1], C. Ropers [2], F. A. Hegmann [1],
[1] University of Alberta, Edmonton, AB, Canada
[2] 4th Physical Institute, University of Göttingen, Göttingen, Germany

Probing ultrafast processes over subpicosecond and picosecond time scales provides fundamental insight into the nature of materials. We have experimentally demonstrated terahertz (THz)-pulse-induced tunneling in a scanning tunneling microscope (THz-STM) to image surfaces with simultaneous nanometer spatial resolution and subpicosecond time resolution [1]. However, the exact mechanism by which ...

Simulation of Electromagnetic Enhancement in Transition Metamaterials using COMSOL

I. Mozjerin[1], T. Gibson[1], and N.M. Litchinitser[1]
[1]Department of Electrical Engineering, The State University of New York at Buffalo, Buffalo, New York, USA

Metamaterials are a new class of artificial materials, which possess various unusual properties. One of these properties is a negative index of refraction produced by setting both the dielectric permittivity ε and the magnetic permeability μ of the material less than zero. Unique electromagnetic phenomena occurring at the interface between negative-index materials and conventional ...