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Sehen Sie, wie die Multiphysik-Simulation in Forschung und Entwicklung eingesetzt wird

Ingenieure, Forscher und Wissenschaftler aus allen Branchen nutzen die Multiphysik-Simulation, um innovative Produktdesigns und -prozesse zu erforschen und zu entwickeln. Lassen Sie sich von Fachbeiträgen und Vorträgen inspirieren, die sie auf der COMSOL Conference präsentiert haben. Durchsuchen Sie die untenstehende Auswahl, verwenden Sie die Schnellsuche, um eine bestimmte Präsentation zu finden, oder filtern Sie nach einem bestimmten Anwendungsbereich.

Sehen Sie sich die Kollektion für die COMSOL Conference 2023 an

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Bengaluru 2023

Munich 2023

Bioscience and Bioengineeringx

Simulation of Transport of Lipophilic Compounds in Complex Cell Geometry

Q.A. Chaudhry[1], M. Hanke[1], and R. Morgenstern[2]
[1]School of Computer Science and Communication, Royal Institute of Technology, Stockholm, Sweden
[2]Karolinska Institutet, Stockholm, Sweden

The mathematical modeling of the diffusion and reaction of toxic compounds in mammalian cells is tough task due to their very complex geometry. The heterogeneity of the cell, particularly the cytoplasm, and the variation of the cellular architecture, greatly affects the behavior of these ... Mehr lesen

A Finite Element Model for The Axon of Nervous Cells

S. Elia[1], P. Lamberti[1], and V. Tucci[1]
[1]Dept. of Electrical and Information Engineering, University of Salerno, Salerno, Italy

This paper proposes a FEM model for a segment of a nervous cell axon, which takes into account, through the so called Hodgkin-Huxley equations, the non linear and time varying dynamics of the membrane surrounding it. A combination with Maxwell equations is performed in a numerical ... Mehr lesen

Modelling of Thermally Induced Electrical Instabilities in Intestine using COMSOL Multiphysics^®

A. Gizzi[1][3], C. Cherubini[1][2], S. Migliori[1][3], and S. Filippi[1][2]
[1]Nonlinear Physics and Mathematical Modeling Lab, Engineering Faculty, University Campus Bio-Medico, Roma, Italy
[2]International Center for Relativistic Astrophysics, University of Rome La Sapienza, Roma, Italy
[3]Alberto Sordi Foundation, Research Institute on Aging, Roma, Italy

Postoperative or paralytic Ileus (PI) is a temporary aftermath of major abdominal surgeries. PI prevents the passage of food throughout the lumen leading to bloating, distension, emesis and pain. A plausible mathematical model for this phenomenology physiologically fine tuned including ... Mehr lesen

COMSOL Multiphysics^® as a Tool for Reducing Animals in Biomedical Research: An Application in Dermatology

F. Rossi[1] and R. Pini[1]
[1]Istituto di Fisica Applicata “Nello Carrara”, Consiglio Nazionale delle Ricerche, Firenze, Italy

In biomedical research the use of animal models gives rise to several ethical problems. COMSOL Multiphysics® may be used as a non-animal technique, very useful in overcoming all these concerns. In this presentation a particular application in dermatology is shown. Bioheat equation ... Mehr lesen

Biosimulation of Normal Pressure Hydrocephalus Using COMSOL Multiphysics^®

K. Shahim[1], J-M. Drezet[1], J-F. Molinari[2], S. Momjian[3], and R. Sinkus[4]

[1]LSMX, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
[2]LSMS, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
[3]University Hospitals of Geneva and University of Geneva, Switzerland
[4]Waves and Acoustics Laboratory, ESPCI, Paris, France

A numerical finite element model of one human brain is built in COMSOL in order to study a particular form of hydrocephalus, the so called Normal Pressure Hydrocephalus (NPH). The geometry of the ventricles and the skull is obtained by Magnetic Resonance Imaging (MRI) and imported in ... Mehr lesen

Designing Polymer Thick Film Intracranial Electrodes for use in Intra-Operative MRI Setting.

G. Bonmassar[1], and A. Golby[2]
[1]AA. Martinos Center, Massachusetts General Hospital, Charlestown, Massachusetts, USA
[2]Department of Neurosurgery, Brigham and Women’s Hospital, Boston, Massachusetts, USA

A new type of MRI compatible intracranial electrode based on Polymer Thick Film (PTF) is presented and studied using COMSOL Multiphysics. The geometry considered was a two-dimensional cross section cut of 5 mm thick electrodes with 5 cm leads on top of a 2×10 cm slab representing ... Mehr lesen

Mathematical Model of Blood Flow in Carotid Bifurcation

E. Muraca[1], V. Gramigna[1], and G. Fragomeni[1]
[1]Department of Experimental Medicine and Clinic, Magna Graecia University of Catanzaro, Catanzaro, Italy

The goal of this research is to provide the medical staff with a numerical system assessment of wall shear stress in carotid bifurcation. Through this model, it will be fundamental to investigate the stress state properties of the surface in contact between the plaque and the artery, and ... Mehr lesen

Simulation of Convection in Water Phantom Induced by Periodic Radiation Heating

H.H. Chen-Mayer[1], and R. Tosh[1]
[1]Ionizing Radiation Division, National Institute of Standards and Technology, Gaithersburg, Maryland, USA

Water calorimetry is employed to establish a primary reference standard for radiation dosimetry by measuring the temperature rises in a water phantom (a cube of about 30 cm x 30 cm x 30 cm) subjected to a beam of ionizing radiation. We use COMSOL Multiphysics to model the system using ... Mehr lesen

Finite Element Modeling a Redox-Enzyme-Based Electrochemical Biosensor

Y. Huang[1], and A. Mason[1]
[1]Electrical and Computer Engineering, Michigan State University, East Lansing, Michigan, USA

This paper describes the modeling of an electrochemical biosensor embedded in a microfluidic channel to determine the concentration of a target biomolecule. The total amount of analyte in the sample can be calculated by integrating the analyte concentration over the duration of the peak ... Mehr lesen

Growth and Remodelling of Intracranial Saccular Aneurysms

A. Di Carlo[1], V. Sansalone[2], A. Tatone[3], and V. Varano[1]
[1]Modelling and Simulation Lab, Università Roma Tre, Roma, Italy
[2]Laboratoire de Mécanique Physique, Université Paris Est, Paris, France
[3]DISAT, Università degli Studi dell’Aquila, L'Aquila, Italy

We present a mechanical model a growing spherical shell suitable for predicting the evolution of a Saccular Cerebral Artery Aneurysms (SCAA). It relies basically on the Kröner-Lee decomposition, used to describe the interplay between the current and the relaxed configuration of body ... Mehr lesen

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