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Smoothing the Path to Simulation-Led Device Design

B. Pryor, and R. Pryor
Pryor Knowledge Systems
Bloomfield Hills, MI

Using modeling software such as COMSOL Multiphysics during the design phase, an approach called “simulation-led design”, allows ideas to be both inspired and validated by the use of simulations. Then, using simulations after the product is designed can shorten the prototype-testing portion of the development process and reduce its cost. This paper provides specifics on the nature of the ...

Reconstruction for Interstitial Diffuse Optical Tomography (iDOT) for Human Prostate

X. Liang, K. Kang-Hsin Wang, and T. Zhu
University of Pennsylvania
Philadelphia, PA

Determination of tissue optical properties distributions is very important for determining light fluence distribution during photodynamic therapy (PDT). In this study, an interstitial diffuse optical tomography (iDOT) system was used to characterize the spatial distribution of optical properties for a series of mathematical phantoms as well as verification measurements in a prostate phantom. ...

Optimization of the Gas Flow in a GEM Tracker with COMSOL and TENDIGEM Development

F. Noto[1,2], V. Bellini[1,2], E. Cisbani[3,4], V. De Smet[1,5], F. Librizzi[6], F. Mammoliti[1,2], and C. Sutera[6]
[1]Dipart. di Fisica ed Astronomia, Università di Catania, Catania, Italy
[2]INFN – Sezione di Catania, Catania, Italy
[3]IINFN – Sezione di Roma - Sanità Group, Roma, Italy
[4]Italian National Institute of Health, Roma, Italy
[5]Haute Ecole Paul-Henri Spaak, ISIB, Bruxelles, Belgium
[6]NFN - Sezione di Catania, Catania, Italy

The Gas Electron Multiplier (GEM) technology has been proven to tolerate rate larger than 50 MHz/cm2 without noticeable aging and to provide the sub millimeter resolution on working chambers up to 45x45 cm2. A new GEM based tracker is under development for the Hall A upgrade at Jefferson Lab. The chambers of the tracker have been designed in a modular way: each chamber consists of 3 adjacent ...

Multi-Domain Analysis of Silicon Structures for MEMS Based-Sensors

N. Bhalla[1], S. Li[2], and D. Chung[1]
[1]Chung Yuan Christian University, Chungli,Taiwan
[2]National Tsing Hua University, Hsinchu, Taiwan

Investigation in this paper aims at performing Mechanical Stress Strain analysis, Thermal, Piezoresistive and Piezoeletric analysis of Silicon Structures using COMSOL. The simulation results have been cross checked by mathematical calculation.

Improving Fuel Usage in Microchannel Based Fuel Cells

P. Fodor, and J. D'Alessandro
Dept. of Physics
Cleveland State University
Cleveland, OH

In this work a miniaturized fuel cell design based on microchannels, into which the liquid fuel and oxidizer streams are fed through T shaped connectors, is optimized for improved fuel usage. This particular design exploits the laminar nature of the fluid flow at small Reynolds numbers to keep the fuel and oxidizer confined in the vicinity of the corresponding electrodes without the need of a ...

Making Cartograms and Using them for Data Acquisition

P. Mercure[1], and R. Haley[2]
[1]The Dow Chemical Company, Midland, MI
[2]ATM Research, Midland, MI

We demonstrate cartogram construction, where a geographical map is distorted to represent some measure, for example population, while trying to keep the shape of regions recognizable. We then apply this cartogram construction technique to optimize thermocouple locations. A heat generation and conduction model is used initialize the cartogram construction algorithm. A uniform distribution of ...

Kinetics of Zebrafish Dorsoventral Patterning

B. Jordan, and P. Müller
Harvard University
Cambridge, MA

The specification of cell types and morphogenesis of many biological systems are regulated by the concentrations of signalling molecules. Many systems employ a pair of secreted short-range activators and long-range inhibitors, and these are widely used to generate complex patterns during development. However, the biophysical mechanisms that regulate the different ranges of activators and ...

Polymer Compositional Profile Controls By-Product Fate from Erodible Endovascular Scaffolds

T. Shazly, and J. Ferdous
Biomedical Eng., Mechanical Eng. Dept.
University of South Carolina
Columbia, SC

Erodible polymeric scaffolds can mitigate long-term risks associated with permanent implants currently used to treat ischemic artery disease. However, safe deployment of erodible scaffolds is predicated on understanding the interactions between evolved material by-products and local biological tissues. We developed an integrated computational model of polymeric scaffold degradation, by ...

Deriving Correction Factors for a Primary Standard for Radiation Dosimetry

R. Tosh, and H. Chen-Mayer
Gaithersburg, MD

Accurate metrology of radiotherapeutic absorbed dose to water requires assessing the radiation induced temperature change. The most direct method for doing this is water calorimetry, for which the established technique involves the use of slender thermistor probes that are sealed within a glass vessel containing high-purity water. The probes and vessel perturb the radiation field, via ...

Microwave Drying of Cellular Ceramic Substrates: A Conjugate Modeling Approach to Understand Surface Moisture Migration

A. Halder, and J. George
Corning, Inc.
Painted Post, NY

Microwave drying processes are critical components in the manufacture of cellular ceramic substrates and filters. The objective of this study is to develop a comprehensive model at a small scale and include all the possible physics that are important during microwave drying processes. Based on the results, conclusions are made on the importance of different factors in drying.

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