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Modeling Light Propagation in Skin for Visualization of Subcutaneous Veins

H. Kwon[1], R. Huancaya[1]
[1]Andrews University, Berrien Springs, MI, USA

Vein visualization systems such as the VeinViewer are vein-contrast enhancement devices that use an infrared camera to highlight blood or the underlying vasculature and project the image in real time onto the skin. Understanding the light propagation in a realistic skin model is critical, but only a few computational models have been developed to account for this particular system. We have ...

Deformation of Biconcave Red Blood Cell in the Dual-Beam Optical Tweezers

Y. Sheng, and L. Yu
University Laval
Quebec City, QC

A biconcave-shaped Red Blood Cell was trapped and deformed in a dual-trap optical tweezers. The two highly focused trapping beams of Gaussian intensity distribution were modeled as background field in the COMSOL Radio Frequency Module. The 3D radiation stress distribution on the cell surface was computed via the Maxwell stress tensor. The 3D deformation of the cell was computed with the ...

Stochastic Diffusion of Calcium Ions Through a Nanopore in the Cell Membrane Created by Electroporation - new

O. Henao[1], V. Gómez[1], I. De La Pava[1], J. Sánchez [1]
[1]Grupo Fisiología Celular y Aplicada, Universidad Tecnológica de Pereira, Pereira, Risaralda, Colombia

We simulated the diffusion of calcium ions through a nanopore created in the cell membrane by electroporation, in presence and absence of the external electric field responsible of the membrane permeabilization. First we solved the set of coupled differential equations that describe the process of ionic diffusion in a 2D nanopore model using the AC/DC Module and the Transport of Diluted Species ...

Effect of Electrical Field Distortion on Particle-Particle Interaction Under DEP

G. Zhang[1], Y. Zhao[1], J. Hodge[1], J. Brcka[2], J. Faguet[2], E. Lee[2]
[1]Clemson University, Clemson, SC, USA
[2]TEL U.S. Holdings, Inc., U.S. Technology Development Center, Austin, TX, USA

In using DEP for particle manipulation, researchers often use a formula to calculate the DEP forces in which the forces are proportional to the particle radius to the third power. This formula assumes that the electrical field, E, will not be affected by the presence of a particle, no matter what the actual size and the dielectric property of the particle are. This work confirms that the ...

Comparing Isotropic and Anisotropic Brain Conductivity Modeling: Planning Optimal Depth-Electrode Placement in White Matter for Direct Stimulation Therapy in an Epileptic Circuit

L. C. Zaragoza[1], B. Hondorp[2], M. A. Rossi[3]
[1]ITESM, Monterrey, Mexico
[2]Rush Medical College, Chicago, IL, USA
[3]Rush University Medical Center, Chicago, IL, USA

The goal of our work was to calculate a patient-specific brain conductivity map for predicting the extent to which direct stimulation therapy can strategically propagate through pathological white matter. Our laboratory developed isotropic and anisotropic human brain finite element method (FEM) models derived from SPGR magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI), ...

Acoustic Field Comparison of High Intensity Focused Ultrasound Using Experimental Characterization and Finite Element Simulation

J. L. Teja[1], A. Vera[1], L. Leija[1]
[1]Department of Electrical Engineering, Cinvestav-IPN, Mexico D.F., Mexico

High Intensity Focused Ultrasound (HIFU) is used as a noninvasive technique of tissue heating and ablation for different medical treatments. This paper presents a quantitative comparison of HIFU acoustic fields experimentally obtained versus simulated acoustic fields. Acoustic field characterization was realized in two HIFU transducers using water as a propagation medium. Also, simulations were ...

Electrical Characterization of Biological Cells on Porous Substrate Using COMSOL Multiphysics®

D. Mondal[1], C. RoyChaudhuri[1]
[1]Department of Electronics and Telecommunication Engineering, Bengal Engineering and Science University, Howrah, West Bengal, India

In this paper, the gross electrical characterization of biological cells on porous substrate is analyzed using COMSOL Multiphysics®. Dynamic electrical characterization during cell growth is used as a non-invasive and label-free technique to understand the growth kinetics of cells. It is observed from the COMSOL simulation that the percentage change in the current density is greater in porous ...

Analysis of 3D Biocompatible Additive Structure Using COMSOL Multiphysics® Software - new

E. Lacatus[1], M. A. Sopronyi[2], G. C. Alecu[1], A. Tudor[1]
[1]Polytechnic University of Bucharest, Bucharest, Romania
[2]INFLPR -National Institute for Laser Plasma and Radiation Physics, Bucharest, Romania

For biocompatible prosthetics, from dental implants up to bone parts, manufacturers have to find the best way to correlate process parameters and the material properties as to meet the unique needs of individuals. Additive manufacturing techniques aim at creating complex biocompatible structures able to overcome the present shortfalls of the metal and metal alloys implants related to ...

A Comparison Between an A-V and V Formulation in Transcranial Magnetic Stimulation

B. Granula[1], K. Porzig[2], H. Toepfer[2], M. Gacanovic[1]
[1]University of Banja Luka, Banja Luka, Bosnia-Herzegovina
[2]Technische Universität Ilmenau, Ilmenau, Germany

The prediction of the exact location and intensity of the electric field induced in the human brain during Transcranial magnetic stimulation is a nontrivial computational task. Numerical simulations of the procedure can be used to acquire first approximations in a safe and controlled environment. In order to make this approach more accessible, it is necessary to reduce computation time as much ...

Multiphysics Modeling and Analysis of DBS Electrodes: Application to Parkinson’s Disease

M.Vidya[1], M. SharatDivya[1], N.Priyadarshini[1], E.R Rajkumar[1]
[1]Division of Biomedical Engineering, Center for Biomedical Engineering Research, School Of Biosciences and Technology, VIT University Vellore, India.

Deep Brain Stimulation (DBS) is a surgical technique that involves surgically implanting Platinum electrode to create an electric field to activate the targeted nerve cells and fibers with minimized side effects. Important stimulation parameters to monitor include temperature, electric field intensity and the current density.This paper gives a Finite Element Model (FEM) for DBS electrode in ...