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Sehen Sie, wie die Multiphysik-Simulation in Forschung und Entwicklung eingesetzt wird

Ingenieure, Forscher und Wissenschaftler aus allen Branchen nutzen die Multiphysik-Simulation, um innovative Produktdesigns und -prozesse zu erforschen und zu entwickeln. Lassen Sie sich von Fachbeiträgen und Vorträgen inspirieren, die sie auf der COMSOL Conference präsentiert haben. Durchsuchen Sie die untenstehende Auswahl, verwenden Sie die Schnellsuche, um eine bestimmte Präsentation zu finden, oder filtern Sie nach einem bestimmten Anwendungsbereich.

Sehen Sie sich die Kollektion für die COMSOL Conference 2023 an

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Bengaluru 2023

Munich 2023

Bioscience and Bioengineeringx

Stochastic Diffusion of Calcium Ions Through a Nanopore in the Cell Membrane Created by Electroporation

O. Henao[1], V. Gómez[1], I. De La Pava[1], J. Sánchez [1]
[1]Grupo Fisiología Celular y Aplicada, Universidad Tecnológica de Pereira, Pereira, Risaralda, Colombia

We simulated the diffusion of calcium ions through a nanopore created in the cell membrane by electroporation, in presence and absence of the external electric field responsible of the membrane permeabilization. First we solved the set of coupled differential equations that describe the ... Mehr lesen

Simulation of Normal and Cancerous T-cell Membrane Electroporation

O. Henao[1], V. Gómez[1], I. De la Pava[1], J. Sánchez[1]
[1]Grupo Fisiología Celular y Aplicada, Universidad Tecnológica de Pereira, Pereira, Risaralda, Colombia

Electroporation is an increase of the cell membrane permeability due to the formation of aqueous pores in it when the cell is under the influence of an intense electric field [1][2]. The formation of such pores in the membrane can be used to enhance the uptake of chemotherapeutic drugs ... Mehr lesen

Simulations of Heat and Mass Transport During Biomass Conversion Processes Using 3D Biomass Particle Models with Realistic Morphology and Resolved Microstructure

P. Ciesielski[1], M. Crowley[1], L. Thompson[1], B. Donohoe[1], D. Robichaud[2], A. Sanders[3], M. Nimlos[2], T. Foust[2]
[1]Biosciences Center, National Renewable Energy Laboratory, Golden, CO, USA
[2]National Bioenergy Center, National Renewable Energy Laboratory, Golden, CO, USA
[3]Quantum Electronics & Photonics Division, National Institute of Standards & Technology, Boulder, CO, USA

Predictive simulations of biomass conversion processes will improve their technical performance and reduce economic uncertainty surrounding industrialization of biofuels production. The majority of present conversion simulations treat the biomass feedstock with simplifying assumptions ... Mehr lesen

Effect of a High Frequency Field on the Electric Double Layer Surrounding a Biomolecule in a Fluid

M. Riou[1], C. Maedler[1], S. Erramilli[1], P. Mohanty[1]
[1]Boston University, Boston, MA, USA

Biosensors based on silicon nanowires are of great interest for ultrasensitive biomolecular recognition of disease specific markers for early stage diagnosis [1]. However, there are limitations on the performance of these nanosensors in solutions at high ionic strength. This is because ... Mehr lesen

Photo-Biological Reactor for Organic Waste Consumption and Hydrogen Production

L. F. de Souza[1]
[1]Universidade Federal do Paraná, Curitiba, Paraná, Brazil

A simple steady-state photo-fermentative biochemical model was developed using the COMSOL Multiphysics'® Transport of Diluted Species physics interface. A dimensionless model seeks optimal physical parameters based on given biochemical parameters found in literature. A parametric sweep ... Mehr lesen

Solving Calcium Spatiotemporal Diffusion Using COMSOL Multiphysics® Software

L. Garber[1,2], G. S. B. Williams[2], W. J. Lederer[2]
[1]Fischell Department of Bioengineering, University of Maryland, Baltimore, MD, USA
[2]Center for Biomedical Engineering & Technology, University of Maryland, Baltimore, MD, USA

This project involves a simplified biological problem that was used to test the potential of COMSOL Multiphysics® software for cardiac myocyte spatial modeling. We made several assumptions to simplify the biological complexity and to highlight the geometrical structures (i.e., lack of ... Mehr lesen

Biofluid-Structural Interaction in Abdominal Aortic Aneurysm for Predicting Timeline to Rupture: The Effect of Hypertension and Aorta Wall Material Properties

K. Cluff[1], H. Mehraein[1], G. Jayakumar[2]
[1]Bioengineering, Wichita State University, Wichita, KS, USA
[2]Industrial & Manufacturing Engineering, Wichita State University, Wichita, KS, USA

An abdominal aortic aneurysm (AAA) is a bulge formed in the large blood vessels that supply blood to the abdomen, pelvis, and legs. A fluid structure interaction model was developed in a 3D aortic aneurysm model, which was constructed from abdominal CT scan images. Combining medical ... Mehr lesen

Analysis of Heat Transfer in a Complex Three Dimensional Structure Fabricated by Additive Manufacturing

C. Settle[1], K. Hoshino[1]
[1]Biomedical Engineering Department, University of Connecticut, Storrs, CT, USA

The goal of this study was to create a three dimensionally designed biomedical device with multiple functionalities and analyze its simulated heat transfer. The device would be fabricated through additive manufacturing; specifically electron beam melting (EBM). EBM has a feature size ... Mehr lesen

Simulation of Bio-medical Waveguide in Mechanical and Optical fields

Y. Xin[1], A. Purniawan[1], L. Pakula[1], G. Pandraud[1], P. J. French[1]
[1]Technology University of Delft, Delft, Netherlands

This paper presents a freestanding waveguide to achieve the goal of detecting anastomosis leakage after colon surgery. The freestanding part is a thin membrane consisting of TiO2 rib and SiN ridge. This freestanding waveguide is designed both mechanically and optically to maintain ... Mehr lesen

Multiphysics Modeling of Electrode-Driven Renal Denervation for Hypertension Treatment

M. Miliani[1], F. Piccagli[1], C. Silvestro[1]
[1]Medtronic Invatec S.p.A., Roncadelle, Italy

Introduction: Chronic arterial hypertension (HTN) is a pathological condition characterized by prolonged high level of arterial blood pressure causing major damages to several human body apparata. Renal sympathetic denervation (RDN) has been found to effectively reduce systemic blood ... Mehr lesen

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