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Finite Element Modeling of Vasoreactivity Using COMSOL Multiphysics® Software - new

J. Parikh[1], A. Kapela[1], N. Tsoukias[1]
[1]Biomedical Engineering Department, Florida International University, Miami, FL, USA

Localized calcium events in the endothelial cells (EC) can modulate smooth muscle cell (SMC) calcium (Ca2+) and membrane potential dynamics through release of endothelium derived hyperpolarizing and relaxing factors. Ca2+ levels in the smooth muscle cell (SMC) determine its contractile state.The underlying complex mechanism regulating the SMC Ca2+ levels and ultimately vessel tone remains poorly ...

Quantification of Porosity Changes Due to Precipitation of Cement Materials with iCP

D. Sampietro [1], E. Abarca [1], M. Bayer [1], S. Jordana [1], J. Molinero [1], T. Tanaka [2], S. Hashimoto [2], T. Iwatsuki [3], H. Onoe [3], H. Saegusa [3]
[1] Amphos 21 Consulting, Barcelona, Spain
[2] Obayashi Corporation, Tokyo, Japan
[3] Japan Atomic Energy Agency, Gifu, Japan

The Japan Atomic Energy Agency (JAEA) is carrying out an URL (Underground Research Laboratory) project in Mizunami city, central Japan. The project is a purpose-built generic URL project that is planned for a scientific study of the deep geological environment in fractured crystalline rock as a basis of research and development for geological disposal of nuclear waste. The concrete material ...

Multiphysics Analysis of a Photobioreactor

L. T. Gritter [1], E. Dunlop [2], J. S. Crompton [1], K. C. Koppenhoefer [1]
[1] AltaSim Technologies, Columbus, OH, USA
[2] Pan Pacific Technologies Pty Ltd, Adelaide, South Australia, Australia

Photo-bioreactors generate biomass by providing a controlled environment for the cultivation of algae due to photosynthesis. Algae cultivation can be controlled through the operating parameters and bioreactor environment to allow for high productivity and the use of systems with large surface-to-volume ratios offers maximum efficiency in the use of light compared to alternative batch systems. ...

Pseudo 3-D Simulation of a Falling Film Microreactor

M. Al-Rawashdeh[1,2], V. Hessel[1,2], P. Löb[1], and F. Schönfeld[1]
[1]Institut für Mikrotechnik Mainz GmbH, Mainz, Germany
[2]Department of Chemical Engineering and
Chemistry, Eindhoven University of Technology, Eindhoven, Netherlands

Gas-liquid falling film microreactors carry out fast exothermic and mass transfer limited reactions. Since the major rate limiting steps occur on the liquid side, it is important to account for a realistic liquid film profile within the reactor simulation. Based on realistic channel geometry and liquid menisci profiles, we describe the liquid film thicknesses, flow velocities, species transport ...

Turbulent Compressible Flow in a Slender Tube

K.O. Lund[1], C.M. Lord[2]
[1]Kurt Lund Consulting, Del Mar, CA, USA
[2]Lord Engineering Corp., Encinitas, CA, USA

Pressure-drop experiments were conducted for the turbulent, compressible flow of air in a small, slender tube, and modeled with COMSOL heat transfer module, and analytically. A scalar integration variable is introduced which integrates the mass velocity [kg/m²s] over the inlet area and iteratively equates this to the input mass flow [kg/s]. For computation, the temperature specification is ...

CO2 Storage Trapping Mechanisms Quantification

A. Nardi[1], E. Abarca[1], F. Grandia[1], J. Molinero[1]
[1]Amphos 21, Barcelona, Spain

The capture and storage of CO2 in deep geological formations is one of the proposed solutions to reduce CO2 emissions to the atmosphere. CO2 is injected as a supercritical fluid deep below a confining geological formation that prevents its return to the atmosphere. In general, four trapping mechanisms are expected, which are of increasing importance through time: (1) structural, (2) residual ...

Analyte Capture from Liquid Samples: Size Matters

M. Weber[1], M. Reed[1]
[1]Yale University, New Haven, CT, USA

Arrays of vertical pillars, Micro Purification Chips, have been widely used for analyte capture from liquid samples [Henderson et. al, 2006], [Toner et. al, 2007], [Stern et. al, 2010]. However exact understanding of the capture efficiency mechanisms has not been previously explained. Here we present a model in COMSOL Multiphysics® which calculates analyte capture efficiency based on initial ...

Simulation and Experimental Analysis of Drug Release Rates from Magnetic Nanocomposite Spheres - new

L. Saeeednia[1], H. Mehraein[2], F. Abedin[1], K. Cluff[2], R. Asmatulu[1]
[1]Department of Mechanical Engineering, Wichita State University, Wichita, KS, USA
[2]Department of Bioengineering, Wichita State University, Wichita, KS, USA

Targeted drug delivery systems have been wildly studied in cancer therapy due to the toxicity of most of chemotherapeutic drugs. Nanoparticles can be attached to the small molecules of the drugs and serve as drug carriers to deliver the drug molecules into the area of interest. In this research, polymeric microspheres containing biodegradable poly(D, L-lactide-co-glycolide) (PLGA), magnetic ...

A Dynamic Simulation of Heterogeneous Catalysis with COMSOL Multiphysics® software

A. K. Patan [1], M. Mekala [1], S. K. Thamida [1],
[1] National Institute of Technology, Warangal, Telengana, India.

Reaction-Diffusion equation is simulated for heterogeneous catalytic reaction involving a porous catalyst particle surrounded by liquid reactants. COMSOL Multiphysics® software along with transport of dilute species module is used for this purpose. Global Variables such as reaction conversion are obtained through post-processing in COMSOL® software itself by evaluation of derived variables.

Optimization of Product from a Segregated Reactor via a Hybrid Modeling Approach

E. Akgün [1], V. Souza [1], J. Appel [1]
Clariant Produkte (Deutschland) GmbH, Burgkirchen, Germany

In the field of chemical reaction engineering chemical kinetics and fluid dynamics are described by various mathematical approaches. Such tools help to shorten the time-to-market of novel products and processes. Thanks to the continuously improving computation power, it is possible to consider the kinetics of chemical reactions as source terms in the Navier-Stokes equations. Even a coupling with ...