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Bioscience and Bioengineering

Simulating Organogenesis in COMSOL Multiphysics®: Parameter Optimization for PDE-based Models

D. Iber[1], D. Menshykau[2], P. Germann[2], L. Lermuzeaux[2,3]
[1]D-BSSE, ETH Zurich, Switzerland, SIB, Basel, Switzerland
[2]D-BSSE, ETH Zurich, Basel, Switzerland
[3]Department of Bioengineering, University of Nice-Sophia Antipolis, Nice, France

Morphogenesis is a tightly regulated process that has been studied for decades. Previously we developed data-based mechanistic models for a range of developmental processes with a view to integrate the available knowledge and to better understand the underlying regulatory logic. In our ... Mehr lesen

An Assessment of the Suitability of the Body and Adult Head Coils for Transmission during Paediatric Magnetic Resonance Imaging

G.R. Cook[1], M.J. Graves[1], F.J. Robb[2], D.J. Lomas[1]
[1]Department of Radiology, University of Cambridge, Cambridge, United Kingdom
[2]General Electric Healthcare Coils, Aurora, Ohio, USA

MRI offers many advantages over other modalities and its lack of ionizing radiation is important for children, but can be limited by the radio-frequency (RF) coils available. This work calculates Specific Absorption Rate (SAR) and homogeneity of the RF transmit field (B1+) when imaging ... Mehr lesen

A Comparison Between an A-V and V Formulation in Transcranial Magnetic Stimulation

B. Granula[1], K. Porzig[2], H. Toepfer[2], M. Gacanovic[1]
[1]University of Banja Luka, Banja Luka, Bosnia-Herzegovina
[2]Technische Universität Ilmenau, Ilmenau, Germany

The prediction of the exact location and intensity of the electric field induced in the human brain during Transcranial magnetic stimulation is a nontrivial computational task. Numerical simulations of the procedure can be used to acquire first approximations in a safe and controlled ... Mehr lesen

Alternate Glucometer Bio-sensor Model based on Ultrasonic MEMS Transceivers

P. Pattnaik[1], S. K. Kamilla [1], Debi Prasad Das[2]
[1]MEMS Design Center, Institute of Technical Education & Research (ITER),Siksha ‘O’ Anushandhan University, Bhubaneswar-751030, Odisha,India
[2]Process Engineering and Instrumentation Cell,Institute of Minerals and Materials Technology (IMMT),Bhubaneswar, Odisha,India

To prevent further complications in diabetes, proper management of blood glucose levels is essential. By using ultrasonic transceivers (both transmit and receive) the glucose level of human blood can be determined. By using this ultrasonic technique miniaturized sensors for non-invasive ... Mehr lesen

Electrohydrodynamic Micropump Modeling for Performance Optimization

A. Mulye[1], S. Potnis[2]
[1]Northeastern University, Boston, MA, USA
[2]VIT, Mumbai, Maharashtra, India

We present an optimized and efficient design of an electrohydrodynamic (EHD) micropump for high performance in microscale and biological applications. We are targeting two major applications, a parylene C design for electrically-actuated medicine delivery, and a silicon-based pump design ... Mehr lesen

Application of the Focused Impedance Method (FIM) to Determine the Volume of an Object within a Volume Conductor

M. A. Kadir[1], S. P. Ahmed[2], G. D. Al Quaderi[3], R. Rahman[2], K. Siddique-e Rabbani[1]
[1]Department of Biomedical Physics & Technology, University of Dhaka, Dhaka, Bangladesh
[2]Department of Physics, Jahangirnagar University, Savar, Dhaka, Bangladesh
[3]Department of Physics, University of Dhaka, Dhaka, Bangladesh

Focused Impedance Method (FIM), a new technique of electrical impedance measurement having high sensitivity in the central region, can sense the change in transfer impedance of an object embedded at a shallow depth within a volume conductor of unchanging background conductivity, using ... Mehr lesen

Simulation of the Electrode-Tissue Interface with Biphasic Pulse Train for Epi-retinal Prosthesis

S. Biswas[1], S. Das[2], M. Mahadevappa[2]
[1]Advanced Technology Development Center, Indian Institute of Technology, Kharagpur
[2]School of Medical Science and Technology, Indian Institute of Technology, Kharagpur

Retinitis Pigmentosa (RP) and Age-related Macular Degeneration (AMD) are diseases causing blindness in a large number of people. In this type of degenerative disease, mostly the photoreceptors are damaged. Thus attempts have been made to electrically stimulate the surviving inner retinal ... Mehr lesen

Electrical Characterization of Biological Cells on Porous Substrate Using COMSOL Multiphysics®

D. Mondal[1], C. RoyChaudhuri[1]
[1]Department of Electronics and Telecommunication Engineering, Bengal Engineering and Science University, Howrah, West Bengal, India

In this paper, the gross electrical characterization of biological cells on porous substrate is analyzed using COMSOL Multiphysics®. Dynamic electrical characterization during cell growth is used as a non-invasive and label-free technique to understand the growth kinetics of cells. It is ... Mehr lesen

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