A Lesson in Cartilage Therapy: Do Chondrocytes Utilize Mechanical Energy from Exercise for Cell Maintenance and Growth?
A. Miller , H. Viljoen , A. Chama , T. Louw ,
 Department of Chemical and Biomolecular Engineering, University of Nebraska - Lincoln, Lincoln, NE, USA
 Department of Chemical Engineering, Stellenbosch University, Stellenbosch, South Africa
- Using COMSOL Multiphysics® Acoustics Module: Chondrocytes modeled attached to a plane (to mimic in vivo constraints) are shown to resonate near 5MHz. At resonance, the mechanical energy density in the nucleus is two times higher than in the cytoplasm. - Impact exercise is modeled as traveling pressure pulses and shown to cause cells to vibrate primarily at the resonance frequency. - Two ...
B. Noailles  , S. Meunier , V. Bruyere 
 RocTool, Savoie Technolac, Module R, France
 SIMTEC, France
In the molding industry, high productivity rate, low energy consumption, large 3D parts, and homogeneous temperature distribution are the main targets. The 3iTech® inductive technology developed by RocTool ensures both good temperature homogeneity and short heating time. Conventionally, to guarantee efficient cooling, a turbulent water flow is directly integrated into the mold. Ideally, to cope ...
Y. K. Hwa 
 National University of Singapore, Singapore
The present work investigates the role of suspended liquid-gas interfaces for applications involving the reduction in flow resistance using the COMSOL multiphysics software. A pressure-driven viscous flow of a liquid through microtubes containing superhydrophobic surfaces patterned with alternating micro-grooves and ribs has been considered. Employing a 3D simulation, a fully-developed laminar ...
Thermal Simulation Of Chemical-Synthesized Thick Film As Thermal Interface Material In Downlight LED
M. J. Wen 
 Universiti Sains Malaysia, Malaysia
As the light output of the LED is strongly dependent on the thermal performance, thermal interface material (TIM) has become an area of interest that can be used to sink more heat out to the ambient. In COMSOL Multiphysics, physics interfaces like joule heating, heat transfer in solid and laminar flow are used to simulate the thermal dissipation with the specific material properties and ...
P. Piskur, W. Tarnowski, and K. Just
Koszalin Technical University, Koszalin, Poland
In this paper a poly-optimization of the design of the electromechanical actuator is presented. The shape of the actuator is defined by the decision variables. The number of decision variables under consideration is up to ten but in the next step while the multi-coils system will be analyzed the number of decision variables will increase up to hundred, so the genetic algorithm has been used. The ...
High Coupling Factor Piezoelectric Materials for Bending Actuators: Analytical and Finite Elements Modeling Results
I.A. Ivan, M. Rakotondrabe, and N. Chaillet
FEMTO-ST Institute, University of Franche-Comte, Besançon, France
New giant piezoelectric factor materials such as PMN-PT and PZN-PT were researched during the last decade and are actually becoming commercially available. As they seem very attractive for actuator designs, we studied their potential in replacing PZT ceramics. In a first comparative approach, we tested a series of classic rectangular composite bimorph structures of different combinations of ...
COMSOL Multiphysics® as a Tool for Reducing Animals in Biomedical Research: An Application in Dermatology
F. Rossi and R. Pini
Istituto di Fisica Applicata “Nello Carrara”, Consiglio Nazionale delle Ricerche, Firenze, Italy
In biomedical research the use of animal models gives rise to several ethical problems. COMSOL Multiphysics® may be used as a non-animal technique, very useful in overcoming all these concerns. In this presentation a particular application in dermatology is shown. Bioheat equation mode and diffusion approximation were used to design a theoretical model of blue LED light interaction with an ...
R. Dufour , C. Wu, F. Bendriaa, V. Thomy, and V. Senez
BioMEMS Group, IEMN, University of Lille Nord de France, Villeneuve d’Ascq, France
This paper presents an Analog to Digital Microfluidic Converter (ADMC) using passive valves and enabling the conversion of a continuous liquid flow into droplets for Electro-Wetting On Dielectric (EWOD) actuation. Valves calibration, geometry characteristics and losses reduction have been optimized using microfluidic application mode of COMSOL Multiphysics®.
K. Lowe [1,2], and Rao V. Arimilli
Oak Ridge National Laboratory, Oak Ridge, TN, USA
Department of Mechanical, Aerospace, and Biomedical Engineering, University of Tennessee, Knoxville, TN, USA
In some power electronic applications the available coolant temperature is close to maximum and controlling operating temperature becomes more challenging, for which new thermal management schemes must be considered. COMSOL predicts the 3D fluid behavior and 3D temperature distribution within an actively cooled power electronic structure. A solution mapping method is implemented to more ...
M. Williams, J. Zito, J. Agashe, A. Sopeju, and D. Arnold
University of Florida, Gainesville, USA
This paper describes the design of a normally closed, electrodynamic microvalve. Magnetic forces between a permanent magnet in the valve cover and a soft magnet in the valve seat hold the valve closed. The combination of electrodynamic actuation and a mechanical restoring spring are used to open the valve. A device model and a design optimization strategy using COMSOL ...