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Design of Novel Recirculation System for Slow Reacting Assays in Microfluidic Domain

N.N. Sharma, and A. Tekawade
Mechanical Engineering Group, Birla Institute of Technology & Science, Pilani, Rajasthan, India

A simple design for a microfluidic flow system for use in mixing or reacting assays with limited sample availability has been proposed and analyzed using COMSOL\'s multiphysics simulation package. The design is based on differential electroosmotic flow concept which has facilitated a number of interesting flow phenomena in micro-domains. For an average potential drop of about 86 kV/m in the ...

Numerical Simulation of a Joule Heating Problem

S.M.F. Garcia[1], and P. Seshaiyer[2]
[1]U.S. Naval Academy, Annapolis, MD, USA
[2]George Mason University, Fairfax, VA, USA

In this work we consider a 1-D mathematical model that describes a heating problem combined with electrical current flows in a body which may undergo a phase change as a result of the heat generated by the current, so-called Joule heating. The model consists of a system of nonlinear partial differential equations with quadratic growth in the gradient. Joule heating is generated by the resistance ...

Expanding Your Materials Horizons

R.W. Pryor
Pryor Knowledge Systems, Inc., Bloomfield Hills, MI, USA

The concept of virtual prototyping can be found linked to many different keywords in the literature: modeling, look-ahead problem solving, etc. This poster paper briefly discusses the potential real benefits that can be realized through pre-build cost savings, minimization of the number of prototype builds, and post-build problem avoidance for physical prototypes and production products. Relative ...

Solving Two-scale Transport Laws During Frying of Foods Using COMSOL Multiphysics

J. Maneerote, and P.S. Takhar
International Center for Food Industry Excellence Texas Tech University, Lubbock, TX, USA

Microscale comprised of the scale of food biopolymers at which biochemical reactions and textural changes take place, and the macroscale was the scale of interaction of polymers with surrounding water, vapor and oil phases. Numerous novel equations such as generalized Darcy’s law based fluid transport equations for various phases; near-equilibrium equation governing phase change from liquid ...

Investigation Of Bone Marrow Stem Cells In The Bone Marrow Niche In An In Vitro System

P. Lezuo, M. Stoddart, and M. Alini
AO Research Institute, Davos, Grison, Switzerland

We aim to develop an in vitro culture system to mimic the human bone marrow stem cell niche in an artificial perfusion bioreactor environment to culture human adult stem cells. State of the art human bone marrow stem cell research shows that even smallest changes in the physical, thermo dynamical or biochemical environment induce a differentiation of human bone marrow stem cells into other cell ...

Numerical Modelling of Compact High Temperature Heat Exchanger

O. Smirnova, T. Fend, and D. Schöllgen
Institut of Solar Research in German Aerospace Agency
Cologne, Germany

For the numeric investigations of the high temperature compact heat exchanger two numeric models with and without the regards of the velocity field development were used. The results of the comparison of the numeric and experimental data confirm the necessity of regarding the velocity field development for the compact heat exchangers. The two-dimensional simulation task with the regard of ...

Development of Mathematical Model for Determining Sound Reduction Index of Building Elements

J. Ratnieks, A. Jakovics, and J. Klavins
University of Latvia
Riga, Latvia

Although we know the physics inside a media where the sound waves propagate, determination of material\'s or structure\'s sound reduction index is not an easy task. The lack of good engineering solutions proves the point. The only reliable way to calculate the sound reduction index is to carry out an experiment.Therefore, the aim of this study is to develop a mathematical model that can ...

Matching 4D Porous Media Fluid Flow GeoPET Data With COMSOL Multiphysics Simulation Results

J. Lippmann-Pipke, J. Kulenkampff, G. Marion, and M. Richter
Helmholtz-Zentrum Dresden
Rossendorf, Institut of Radiochemistry
Research Site Leipzig
Reactive Transport Division
Leipzig, Germany

We apply COMSOL Multiphysics for reproducing our experimental observations of fluid flow and transport processes in geological media. Our experimental GeoEPT-method allows the 4D monitoring of transport processes in geological material on laboratory scale. Explicitly we import “realistic structures” from geologic samples scanned by means of computer tomography (CT) as stl-files into COMSOL ...

Numerical Experiments for Thermally-induced Bending of Nematic Elastomers with Hybrid Alignment

L. Teresi[1], and A. DeSimone[2]
[1]LaMS - Modeling & Simulation Lab, University Roma Tre, Roma, Italy
[2]SISSA - International School for Advanced Studies, Trieste, Italy

We deal with Liquid Crystal Elastomers (LCEs) having hybrid alignment (HNEs), that is, fabricated with a given non-homogeneous nematic orientation. For such a materials, permanent distortions induced by deswelling can be compensated by those resulting from cooling below the transition temperature, thus yielding the possibility of producing temperature-driven actuators. Here, we simulate the ...

A High-Efficiency Micro-Channel Regenerative Heat Exchanger for Fluid Processing

O. Yildirim, and Z. Guo
Intellectual Ventures Laboratories
Bellevue, WA

Regenerative heat exchangers (RHX) find widespread applications in liquid food or pharmaceutical processing as well as in reaction engineering. Whereas \"large\" RHX systems have been in use for a long time, their smaller micro-channel counterparts are a more recent area of interest. Here, we describe the design and development of a novel micro-channel counter-current regenerative heat ...

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